Clairju is an extract of the fruit of Prunus domestica (prunes).  The name is coined from the French word “claire” which means clear and “jus” which means juice of a fruit. The prune fruit contains compounds such as beta-carotene, beta-cryptoxanthin, lutein, neochlogenic acid, and vitamins and minerals such as Vit. A, C, E and B complex. It is a product of Ichimaru Pharcos of Japan.

Background:

Most skin whitening agents target the inhibition of melanin synthesis through the enzyme tyrosinase. For this reason, these whitening agents are often called “tyrosinase inhibitors.” But in this novel “melanin diet” theory, it argues that melanin is synthesized because the skin needs it for protection against the adverse effects of sunlight.

On the other hand, the phagocytotic action of keratinocytes consume synthesized melanin from the neighboring melanocytes. Because of this action, keratinocytes themselves turn dark (black).

Clairju works to “curb” the phagocytotic appetite of keratinocytes to eat up synthesized melanin which are contained in melanosomes. Technically, this means the inhibition of uptake of melanosomes into the keratinocytes.

Back in the late ’90s when researchers and developers of whitening agents scrambled to come up with an effective skin whitening agent, studies were conducted and possibilities were looked into in inhibiting the different stages of the synthesis of melanin. One possibility then that they were looking into was the inhibition of the uptake of melanosomes into the keratinocytes. Back in those days, this was not yet a reality, but with the development of Clairju, that vision is now realized.

Clairju can work in conjunction with other whitening agents or tyrosinase inhibitors to produce a highly effective whitening product.

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