Ceramix Plus

Ceramides are a family of lipids composed of a sphingoid base and a fatty acid. In the skin, they are mainly present in the stratum corneum where, with cholesterol and free fatty acids, they constitute the inter-corneocyte lipids. They are a naturally-occurring lipids that make up about 30% to 50% of the skin's outer layer. They act as the "mortar" between the skin cells, creating a protective barrier that locks in moisture and keeps environmental irritants out. 

Ceramix Plus is a blend of 3 kinds of ceramides plus phytosphingosine. It contains the ff. ceramides in significantly high concentrations:

Ceramide EOP (Ceramide I)

Ceramide I (EOP) is a product of yeast fermentation, identical human skin lipids, including a three-dimensional stereochemical structure. Its molecule contains a Phytosphingosine backbone conjugated with a saturated ω-hydroxy acid (a fatty acid with 27 carbons) that is esterified with stearic acid.

Acylceramides such as Ceramide EOP play a significant role in the organization of the stratum corneum lipids and, consequently, in balancing the requirement for relatively impervious skin with the need for flexibility. Ceramide 1 acts as a natural rivet molecule for optimal skin flexibility and will improve barrier cohesion, i.e., "cement" function.

Ceramide EOP reinforces the natural lipid barrier, improving the condition of dry, aging, or damaged skin.

Ceramide NP (Ceramide III)

Ceramide III (NP) is produced in a patented bio-fermentation process and has the same chemical structure as the human skin. They restructure the bonding substance of the cell bonds and the protective function of the human sebum (natural protective barrier).

Ceramide 3 supports the renewal of the natural protective layer of the skin and forms an effective barrier against moisture loss. This human-skin-identical molecule is particularly for long-term protection and repair of sensitive and dry skin.

Ceramide AP (VI)

Ceramide AP consists of a Phytosphingosine backbone connected with a long chain of alpha-hydroxy stearic acid (AHA). Thanks to alpha-hydroxy acid in the structure, this ceramide has an additional attractive property for skin care preparations. Like other AHAs, it acts as a gentle peel, promoting the natural desquamation process and exposing an even, smoother and fresher complexion.

With its mild action, Ceramide AP is suitable for sensitive skin. It lessens fine lines and wrinkles, eliminates dead and dull cells, and improves barrier function—an ideal ingredient for antiaging skincare products.

Phytosphingosine

Phytosphingosine is plant-derived sphingosine, an integral part of ceramides and naturally occurring in the skin. It is part of the group of complex lipids that are called sphingoid bases. Sphingoid bases and ceramides are present in high levels and are the crucial components of the stratum corneum, playing an important role in the skin's natural defense system and inhibit the development of various microorganisms.

Phytosphingosine is obtained biotechnologically through yeast fermentation. Its unique and excellent properties as an antimicrobial and anti-inflammatory agent demonstrate efficient synergistic effects in the treatment of the skin with acne and inflammation with significant microbial imbalance. It boosts repair processes in damaged skin and replenishes the barrier.

It has anti-inflammatory and anti-microbial activities (effective against Propionibacterium acnes and Staphylococcus aureus). It shows excellent results in acne treatment. Clinical studies that have been performed on acne patients demonstrate the prospect of phytosphingosine to enhance or complement existing acne therapies.